SM-TF Data

"Organism", "Protein", and "Gene" of TFs are taken from the UniProt database.
TFs from human and mouse are linked to the TFClass database.
TFs from E. coli are linked to the RegulonDB.
20 out of 32 Druggable TFs (marked by DT in the "UniProt" column), extracted from the DrugBank database, are available in the SM-TF database. A table containing all the Druggable TFs and their corresponding approved drugs is provided HERE.

UniProt Organism Protein Gene Small Molecules PDBs TFClass /
RegulonDB
SM-TF
Q99814 Homo sapiens Endothelial PAS domain-containing protein 1 EPAS1 2XY, 018, 020, 0X3, 0XB 3F1O, 3H7W, 3H82, 4GHI, 4GS9 1.2.5.1.7 link
DTP04150 Homo sapiens Glucocorticoid receptor NR3C1 DEX, 486, DAY, GW6, 866, JZR, JZS, JZN, NN7, LSJ, 29M, MOF, HCY 1M2Z, 1NHZ, 3BQD, 3CLD, 3E7C, 3K22, 3K23, 4CSJ, 4LSJ, 4MDD, 4P6W, 4P6X 2.1.1.1.1 link
DTP08235 Homo sapiens Mineralocorticoid receptor NR3C2 1CA, C0R, AS4, STR, PDN, SNL, LD1, LD2, WFF, WFG, HFN 1Y9R, 2A3I, 2AA2, 2AA6, 2AAX, 2AB2, 3VHV, 3WFF, 3WFG, 4PF3 2.1.1.1.2 link
DTP06401 Homo sapiens Progesterone receptor PGR STR, R18, NDR, MOF, T98, AS0, 486, NOG, 30X, GKK, WOW, OR8, ORB, ORC, A2K, 2S0 1A28, 1E3K, 1SQN, 1SR7, 1ZUC, 2OVH, 2OVM, 2W8Y, 3D90, 3G8O, 3HQ5, 3KBA, 3ZR7, 3ZRA, 3ZRB, 4A2J, 4APU, 4OAR 2.1.1.1.3 link
DTP10275 Homo sapiens Androgen receptor AR ZK5, R18, 198, TES, 17H, FHM, BHM, LGD, CA4, 2MI, ICO, K10, RB1, NK, 4HY, T3, FLF, ENM, YLO, 056, YLQ, B5R, 3B6, B66, B67, B68, RLJ, RLL, PK0, PK1, 30Z, 17W, MXD, HFT 1GS4, 1XOW, 1Z95, 2AM9, 2AMB, 2AX8, 2AX9, 2HVC, 2OZ7, 2PIO, 2PIP, 2PIQ, 2PIR, 2PIT, 2PIV, 2PIX, 2PNU, 2YLO, 2YLP, 2YLQ, 3B5R, 3B65, 3B66, 3B67, 3B68, 3L3X, 3RLJ, 3RLL, 3V49, 3V4A, 3ZQT, 4HLW, 4K7A, 4OHA 2.1.1.1.4 link
DTP03372 Homo sapiens Estrogen receptor ESR1 ZTW, ETC, GW5, E4D, PTI, 244, AIH, AIU, AIJ, AIT, AEJ, CM4, CM3, 689, L4G, 458, 17M, 459, T3O, DRQ, I0G, IOG, IOK, C3D, EZT, WST, A48, DC8, KN2, GEN, EI1, JJ3, EED, EES, ODE, HZ3, 1HP, PIQ, RAL, KN1, LLB, LLC, EEU, MLZ, SFG, 369, DES, OHT, J2Z, J3Z, 4OH, KN0, ESL, Q97, SRR, 2OH, 0CZ, 0D1, EST, 0L8, 1GM, 1GQ, 1GR, 1GS, 1GJ, 1GT, 1GU, KN3, 1GV, 15Q, TPO, 27E, 27G, 27H, 27J, 27K, 27L, XDH, 27M, 27N, STL, FSV, ESE 1GWQ, 1L2I, 1R5K, 1SJ0, 1UOM, 1X7E, 1XP1, 1XP6, 1XP9, 1XPC, 1XQC, 1YIM, 1YIN, 1ZKY, 2AYR, 2B1V, 2B1Z, 2FAI, 2G44, 2G5O, 2I0J, 2IOG, 2IOK, 2OUZ, 2P15, 2POG, 2Q6J, 2Q70, 2QA6, 2QA8, 2QAB, 2QE4, 2QGT, 2QGW, 2QH6, 2QR9, 2QSE, 2QXM, 2QXS, 2QZO, 2R6W, 2R6Y, 2YAT, 3CBO, 3CBP, 3DT3, 3ERD, 3ERT, 3HLV, 3HM1, 3L03, 3OS8, 3Q95, 3Q97, 3UU7, 3UUA, 3UUC, 3UUD, 4DMA, 4IU7, 4IUI, 4IV2, 4IV4, 4IVW, 4IVY, 4IW6, 4IW8, 4IWC, 4IWF, 4JC3, 4MG5, 4MG6, 4MG7, 4MG8, 4MG9, 4MGA, 4MGB, 4MGC, 4MGD, 4PP6, 4PPP, 4PPS 2.1.1.2.1 link
DTQ92731 Homo sapiens Estrogen receptor beta ESR2 ETC, MON, GEN, 272, 338, 797, 397, 697, 244, 041, 4NA, 196, 789, OHT, FBR, I0G, JJ3, 555, 3AS, YJD, SU4, DC8, EST, WV7, W14, W23 1L2J, 1NDE, 1QKM, 1U3Q, 1U3R, 1U3S, 1U9E, 1X76, 1X78, 1X7B, 1YY4, 1YYE, 1ZAF, 2FSZ, 2GIU, 2I0G, 2JJ3, 2NV7, 2QTU, 2YJD, 2YLY, 2Z4B, 3OLL, 3OMO, 3OMP, 3OMQ 2.1.1.2.2 link
P11474 Homo sapiens Steroid hormone receptor ERR1 ESRRA 047, 5FB 2PJL, 3K6P 2.1.1.2.3 link
DTP62508 Homo sapiens Estrogen-related receptor gamma ESRRG 2OH, TXF, 1BA, OHT, 43M, 1OH, BPZ 2E2R, 2EWP, 2GPP, 2GPU, 2P7A, 2ZAS, 2ZKC 2.1.1.2.5 link
DTP10276 Homo sapiens Retinoic acid receptor alpha RARA BMS, REA, EQN, EQO, LUF 1DKF, 3A9E, 3KMR, 3KMZ, 4DQM 2.1.2.1.1 link
DTP10826 Homo sapiens Retinoic acid receptor beta RARB TTB, REA, 1NY, JYH, JYI 4DM6, 4DM8, 4JYG, 4JYH, 4JYI 2.1.2.1.2 link
DTP13631 Homo sapiens Retinoic acid receptor gamma RARG 394, 961, 184, 564, LMU, 156, 254, REA 1EXA, 1EXX, 1FCX, 1FCY, 1FCZ, 1FD0, 2LBD 2.1.2.1.3 link
DTP10827 Homo sapiens Thyroid hormone receptor alpha THRA IH5, T3, B72, 4HY 1NAV, 2H79, 3ILZ, 3JZB, 4LNX 2.1.2.2.1 link
DTP10828 Homo sapiens Thyroid hormone receptor beta THRB PFA, IH5, G24, 442, T44, OEF, LEG, 4HY, T3, B72 1N46, 1NAX, 1Q4X, 1R6G, 1Y0X, 2J4A, 2PIN, 3D57, 3GWS, 3IMY 2.1.2.2.2 link
Q14995 Homo sapiens Nuclear receptor subfamily 1 group D member 2 NR1D2 HEM, COH 3CQV, 4N73 2.1.2.3.2 link
DTP11473 Homo sapiens Vitamin D3 receptor VDR KH1, VDX, EB1, MC9, TX5, C33, OCC, C3O, O1C, MVD, TEJ, 2MV, 23R, 3EV, CA9, EIM, DS2, DS3, DS6, MCZ, COV, 0CO, ZNE, FMV, ZYD, VHW, DS5, 6DS, DS4, ED9, 0VQ, TEY, TFY 1IE8, 1IE9, 1S0Z, 1S19, 1TXI, 2HAM, 2HAR, 2HAS, 2HB7, 2HB8, 3A2J, 3A3Z, 3A40, 3A78, 3AUR, 3AX8, 3AZ1, 3AZ2, 3AZ3, 3B0T, 3CS4, 3CS6, 3KPZ, 3OGT, 3P8X, 3VHW, 3W0A, 3W0C, 3W0Y, 3WGP, 4G2I, 4ITE, 4ITF 2.1.2.4.1 link
DTO75469 Homo sapiens Nuclear receptor subfamily 1 group I member 2 NR1I2 HYF, SRL, RFP, 444, CDZ, PNU, 2Q4 1M13, 1NRL, 1SKX, 2O9I, 2QNV, 3R8D, 4NY9 2.1.2.4.2 link
Q14994 Homo sapiens Nuclear receptor subfamily 1 group I member 3 NR1I3 CI2, CID 1XV9, 1XVP 2.1.2.4.3 link
DTQ07869 Homo sapiens Peroxisome proliferator-activated receptor alpha PPARA AZ2, CPQ, 544, 471, MMB, 735, REW, S44, ET1, CTM, RO7, 7HA, NKS, IL2, 13M, WY1 1I7G, 1K7L, 1KKQ, 2NPA, 2P54, 2REW, 2ZNN, 3ET1, 3FEI, 3G8I, 3KDT, 3KDU, 3SP6, 3VI8, 4BCR 2.1.2.5.1 link
DTQ03181 Homo sapiens Peroxisome proliferator-activated receptor delta PPARD 433, 331, B7G, VCA, GNI, 1FA, WLM, 08S, BOG, Z00, K55, 401, L41, DY6, ET1, EPA, D32, 3OZ, 3EQ, JZR, IL2, GW0 1GWX, 1Y0S, 2AWH, 2J14, 2Q5G, 2XYJ, 2XYW, 2XYX, 2ZNP, 2ZNQ, 3D5F, 3DY6, 3ET2, 3GWX, 3GZ9, 3OZ0, 3PEQ, 3SP9, 3TKM 2.1.2.5.2 link
DTP37231 Homo sapiens Peroxisome proliferator-activated receptor gamma PPARG 570, AZ2, 544, YPA, DRF, C01, BRL, 3EA, EHA, RO0, SP0, SP3, 208, NSI, DRY, DRD, DRJ, DRH, AJA, C03, GW4, 240, 241, NZA, SF1, SF2, PLB, L92, 9HO, 243, HXA, 4HD, 5HE, 4R8, 6OB, 6OC, P1B, YFE, GSH, PTG, OCX, C08, S44, HID, SRO, MYI, OCR, IMN, NRO, M7S, M7R, MC5, GW9, KRC, ZAA, YRG, GRR, LNA, LNB, ET0, ET1, CTM, Z12, RO7, 2PQ, D30, DKD, ZZH, UNT, Z27, 538, CEK, 5BC, XDH, XDI, ZXG, XPT, 486, MLO, HIG, XCX, M0T, LU2, MYR, 3T0, 082, DKA, 17L, 21L, 24L, J35, J53, TLS, EK1, EK8, TBY, T9T, JJA, YFD, YFB, RRG, RRH, KNA, FCM, 0W3, 14R, STL, AXY, LRG, 072 1FM9, 1I7I, 1K74, 1KNU, 1NYX, 1ZEO, 1ZGY, 2ATH, 2F4B, 2FVJ, 2G0G, 2G0H, 2GTK, 2HFP, 2HWQ, 2HWR, 2I4J, 2I4P, 2OM9, 2P4Y, 2POB, 2Q59, 2Q5P, 2Q5S, 2Q61, 2Q6R, 2Q6S, 2Q8S, 2VSR, 2VST, 2VV0, 2VV1, 2VV2, 2VV3, 2VV4, 2XKW, 2YFE, 2ZK2, 2ZK3, 2ZK6, 2ZNO, 2ZVT, 3ADT, 3ADV, 3ADW, 3ADX, 3AN3, 3AN4, 3B0Q, 3B0R, 3B1M, 3BC5, 3CDP, 3CDS, 3CWD, 3ET0, 3ET3, 3FEJ, 3FUR, 3G9E, 3GBK, 3H0A, 3HO0, 3HOD, 3IA6, 3K8S, 3KMG, 3LMP, 3NOA, 3OSI, 3OSW, 3PBA, 3PO9, 3QT0, 3R5N, 3R8A, 3R8I, 3S9S, 3SZ1, 3T03, 3TY0, 3U9Q, 3V9T, 3V9V, 3V9Y, 3VJH, 3VJI, 3VN2, 3VSO, 3VSP, 3WJ4, 3WJ5, 3WMH, 4A4V, 4A4W, 4E4K, 4E4Q, 4EM9, 4F9M, 4FGY, 4HEE, 4JAZ, 4JL4, 4L98, 4PRG 2.1.2.5.3 link
P35398 Homo sapiens Nuclear receptor ROR-alpha RORA CLR, C3S 1N83, 1S0X 2.1.2.6.1 link
P51449 Homo sapiens Nuclear receptor ROR-gamma RORC DGX, HC2, HC9, HC3, 444, NBH, 39K, 3QQ 3B0W, 3KYT, 3L0J, 3L0L, 4NB6, 4NIE, 4QM0, 4WLB 2.1.2.6.3 link
Q13133 Homo sapiens Oxysterols receptor LXR-alpha NR1H3 444, 965, O90, O40 1UHL, 3IPQ, 3IPS, 3IPU 2.1.2.7.1 link
P55055 Homo sapiens Oxysterols receptor LXR-beta NR1H2 CO1, 965, 44B, 444, 61X, G58, 0KS, 0KT 1P8D, 1PQ6, 1PQ9, 1UPV, 3KFC, 3L0E, 4DK7, 4DK8 2.1.2.7.2 link
DTQ96RI1 Homo sapiens Bile acid receptor NR1H4 FEX, MUF, 064, O62, 33Y, 643, 708, 82X, 088, 635, OKH, OKI, OLF, OMK, OMM, OOF, OOK, P88, 89P, 59G, 37G, 034, IVM 1OSH, 3BEJ, 3DCT, 3DCU, 3FLI, 3FXV, 3GD2, 3HC5, 3HC6, 3L1B, 3OKH, 3OKI, 3OLF, 3OMK, 3OMM, 3OOF, 3OOK, 3P88, 3P89, 3RUT, 3RUU, 3RVF, 4WVD 2.1.2.7.3 link
DTP19793 Homo sapiens Retinoic acid receptor RXR-alpha RXRA 9CR, REA, HXA, BM6, L79, F15, 3TN, 4TN, 5TN, P26, 21P, TBY, 2E3, 9RA, T9T, CHZ, BGV, LX8, RHN, MLO, 1O8, 29V, R4M, K09, K08, 2QO, 2VR, 2VP, 2VZ, 2W0 1FM6, 1G5Y, 1MV9, 1MVC, 1RDT, 1XVP, 2P1T, 2P1U, 2P1V, 2ZXZ, 2ZY0, 3E94, 3FUG, 3H0A, 3KWY, 3NSQ, 3OZJ, 3PCU, 3R2A, 3R5M, 4K4J, 4M8E, 4M8H, 4N5G, 4N8R, 4OC7, 4POH, 4POJ, 4PP3, 4PP5 2.1.3.1.1 link
DTP28702 Homo sapiens Retinoic acid receptor RXR-beta RXRB LG2, MEI 1H9U, 1UHL 2.1.3.1.2 link
P41235 Homo sapiens Hepatocyte nuclear factor 4-alpha HNF4A MYR 1PZL 2.1.3.2.1 link
Q14541 Homo sapiens Hepatocyte nuclear factor 4-gamma HNF4G PLM 1LV2 2.1.3.2.2 link
Q9Y466 Homo sapiens Nuclear receptor subfamily 2 group E member 1 NR2E1 MAL 4XAJ 2.1.3.3.1 link
P22736 Homo sapiens Nuclear receptor subfamily 4 group A member 1 NR4A1 TMY, T94, ZJ0 3V3Q, 4JGV, 4KZI 2.1.4.0.1 link
Q13285 Homo sapiens Steroidogenic factor 1 NR5A1 P0E, PEF, PIZ, PIK 1YOW, 1ZDT, 4QJR, 4QK4 2.1.5.0.1 link
O00482 Homo sapiens Nuclear receptor subfamily 5 group A member 2 NR5A2 P6L, EPH, P3A, 470, PLC 1YOK, 1YUC, 1ZDU, 3PLZ, 4DOS 2.1.5.0.2 link
P41182 Homo sapiens B-cell lymphoma 6 protein BCL6 Z88, Z89, RBT 3LBZ, 4CP3 2.3.3.22.2 link
Q03164 Homo sapiens Histone-lysine N-methyltransferase 2A KMT2A SAH 2W5Y 2.6.1.0.4 link
Q92794 Homo sapiens Histone acetyltransferase KAT6A KAT6A ACO 2OZU 2.7.3.0.3 link
Q9Y468 Homo sapiens Lethal(3)malignant brain tumor-like protein 1 L3MBTL1 MES, MLY, MLZ, P8H, UWN 1OYX, 1OZ2, 2RHU, 2RHY, 3P8H, 3UWN 2.7.4.0.1 link
Q15475 Homo sapiens Homeobox protein SIX1 SIX1 MAL 4EGC 3.1.6.1.1 link
O75376 Homo sapiens Nuclear receptor corepressor 1 NCOR1 486 3H52 3.5.1.2.1 link
Q02078 Homo sapiens Myocyte-specific enhancer factor 2A MEF2A BXL 3MU6 5.1.1.1.1 link
P04637 Homo sapiens Cellular tumor antigen p53 TP53 P83, X0U, X0V, X0W, QC5, P84, P86, NXG, P74, P51, P96 2VUK, 2X0U, 2X0V, 2X0W, 3ZME, 4AGL, 4AGM, 4AGN, 4AGO, 4AGP, 4AGQ 6.3.1.0.1 link
O00255 Homo sapiens Menin MEN1 0BR, CHD, 0RO, 0RT, 2S6, 2VK, 2S7, 2S9, 2SE, 2SF, 3XW, 3XY 3U88, 4GQ3, 4GQ4, 4OG3, 4OG4, 4OG5, 4OG6, 4OG7, 4OG8, 4X5Y, 4X5Z N/A link
O15164 Homo sapiens Transcription intermediary factor 1-alpha TRIM24 ALY 3O36 N/A link
O60341 Homo sapiens Lysine-specific histone demethylase 1A KDM1A FAD, FAD-TCF, FAD-3PL, FAD-TCA, FAD-M84, M80, F2N, FAJ, 2PF, 12F, THG, D69, D70, D73, D51, D52, FAD-M8A 2DW4, 2XAG, 2XAH, 2XAJ, 2XAQ, 2XAS, 2Z3Y, 2Z5U, 3ABT, 3ABU, 4KUM, 4UV8, 4UV9, 4UVA, 4UVB, 4UVC, 4UXN N/A link
P22392 Homo sapiens Nucleoside diphosphate kinase B NME2 DA-DG, DG, GDP 3BBB, 3BBF N/A link
P51532 Homo sapiens Transcription activator BRG1 SMARCA4 MB3 3UVD N/A link
Q13363 Homo sapiens C-terminal-binding protein 1 CTBP1 NAD, KMT, 3CR, NAI, PPY 1MX3, 4LCE, 4U6Q, 4U6S N/A link
Q92793 Homo sapiens CREB-binding protein CREBBP ALY, MB3, DMS, 3PF, KRG, TYL, 2LK, 2LL, 2LN, 2LO, 15E, 2O3, 2O4 3P1C, 3P1D, 3P1E, 3P1F, 3SVH, 4A9K, 4NR4, 4NR5, 4NR6, 4NR7, 4NYV, 4NYW, 4NYX N/A link
Q96T88 Homo sapiens E3 ubiquitin-protein ligase UHRF1 UHRF1 36X 4QQD N/A link
Q9NRY4 Homo sapiens Rho GTPase-activating protein 35 ARHGAP35 GNP 3C5H N/A link
Q9UQR0 Homo sapiens Sex comb on midleg-like protein 2 SCML2 MLZ 2VYT N/A link
P03023 Escherichia coli Lactose operon repressor lacI NPF, IPT, 145, HEZ 1EFA, 2P9H, 2PE5, 3EDC ECK120012762 link
P07026 Escherichia coli Regulatory protein SdiA sdiA HTF 2AVX ECK120011856 link
P09546 Escherichia coli Bifunctional protein PutA putA 2OP, SO2, PRO, FAD, HYP, TFB 1TJ1, 2FZM, 2FZN, 3E2Q, 3E2R ECK120012029 link
P0A6D0 Escherichia coli Arginine repressor argR ARG 1XXA ECK120011670 link
P0A6Z6 Escherichia coli Nickel-responsive regulator nikR 3CM 2HZA ECK120023539 link
P0A881 Escherichia coli Trp operon repressor trpR TRP 1JHG ECK120012176 link
P0A8U6 Escherichia coli Met repressor metJ SAM 1CMC ECK120048948 link
P0A9E0 Escherichia coli Arabinose operon regulatory protein araC FCB, ARA 2AAC, 2ARC ECK120012316 link
P0ACI3 Escherichia coli Xylose operon regulatory protein xylR XYS 4FE7 ECK120013786 link
P0ACI6 Escherichia coli Regulatory protein AsnC asnC ASN 2CG4 ECK120013010 link
P0ACJ8 Escherichia coli cAMP-activated global transcriptional regulator CRP crp CMP 4HZF ECK120011235 link
P0ACP7 Escherichia coli HTH-type transcriptional repressor PurR purR HPA, GUN, 6MP, ADE 1JFT, 1WET, 2PUA, 2PUB ECK120012854 link
P0ACU2 Escherichia coli HTH-type transcriptional regulator RutR rutR URA 4JYK ECK120033905 link
P16528 Escherichia coli Acetate operon repressor iclR GOA, PYR 2O99, 2O9A ECK120011897 link
P24242 Escherichia coli HTH-type transcriptional regulator AscG ascG FRU 3BRQ ECK120026318 link
P27111 Escherichia coli HTH-type transcriptional regulator CynR cynR AZI 3HFU ECK120013065 link
P27245 Escherichia coli Multiple antibiotic resistance protein MarR marR SAL 1JGS ECK120013191 link
P37344 Escherichia coli Psp operon transcriptional activator pspF ANP, AMP, ATP, ADP 2C99, 2VII, 4QNR, 4QOS ECK120011400 link
P76016 Escherichia coli PTS-dependent dihydroxyacetone kinase operon regulatory protein dhaR ADP 4LRZ ECK120015690 link
P0A8V6 Escherichia coli O157:H7. Fatty acid metabolism regulator protein fadR COA-MYR 1H9G ECK120011824 link
Q8XBD0 Escherichia coli O157:H7. Transcriptional regulator of ftsQAZ gene cluster sdiA 480, 482, LAE 4Y13, 4Y15, 4Y17 ECK120011856 link
P06537 Mus musculus Glucocorticoid receptor Nr3c1 DEX 3MNP 2.1.1.1.1 link
P19091 Mus musculus Androgen receptor Ar 4HY, DHT 2QPY 2.1.1.1.4 link
P62509 Mus musculus Estrogen-related receptor gamma Esrrg DES, CHD, OHT 1S9P, 1S9Q 2.1.1.2.5 link
P22605 Mus musculus Retinoic acid receptor beta Rarb REA 1XDK 2.1.2.1.2 link
O35627 Mus musculus Nuclear receptor subfamily 1 group I member 3 Nr1i3 TCD, ATE 1XLS, 1XNX 2.1.2.4.3 link
Q9Z0Y9 Mus musculus Oxysterols receptor LXR-alpha Nr1h3 L05, LO2, LX2 2ACL, 3FAL, 3FC6 2.1.2.7.1 link
P28700 Mus musculus Retinoic acid receptor RXR-alpha Rxra OLA, REA, 754 1DKF, 1XDK, 3A9E 2.1.3.1.1 link
P33242 Mus musculus Steroidogenic factor 1 Nr5a1 DR9, PEF, P42 1YMT, 1YP0, 3F7D 2.1.5.0.1 link
Q62227 Mus musculus Nuclear receptor subfamily 0 group B member 2 Nr0b2 MAL 4NUF 2.1.7.0.2 link
Q96EQ9 Mus musculus Histone-lysine N-methyltransferase PRDM9 Prdm9 SAH 4C1Q 2.3.4.0.71 link
P02340 Mus musculus Cellular tumor antigen p53 Tp53 TRS, FLC 2IOI, 3EXJ 6.3.1.0.1 link
O05521 Bacillus subtilis Redox-sensing transcriptional repressor Rex rex NAD, ATP 2VT2, 2VT3 N/A link
O34835 Bacillus subtilis Transcription factor FapR fapR MLC 2F3X N/A link
O34994 Bacillus subtilis Transcriptional repressor CcpN ccpN ADP, ANP 3FWR, 3FWS N/A link
P11065 Bacillus subtilis HTH-type transcriptional regulator Hpr hpr 1PE, P6G, PGE 2FXA N/A link
P17893 Bacillus subtilis Arginine repressor argR ARG 2P5M N/A link
P39779 Bacillus subtilis GTP-sensing transcriptional pleiotropic repressor CodY codY ILE, VAL 2B18, 2HGV N/A link
P94426 Bacillus subtilis HTH-type transcriptional regulatory protein GabR gabR LLP 4N0B N/A link
P96711 Bacillus subtilis Arabinose metabolism transcriptional repressor araR ARB 3TB6 N/A link
P13053 Rattus norvegicus Vitamin D3 receptor Vdr VDZ, VD1, VD2, VD4, VD5, YR3, VDA, VDB, NYA, TT2, MI4, JB1, JC1, TEJ, ICJ, YR4, 10S, 10R, YS2, YS3, YSD, YS5, 5YI, YI2, VDX, YI3, YI4, TKA, TK3, TKD, W07, W12, O11, T08, 4OA, 3KL, LOA, LHP, YA1, YA2 1RJK, 1RKG, 1RKH, 2O4J, 2O4R, 2ZFX, 2ZL9, 2ZLA, 2ZMH, 2ZMI, 2ZMJ, 2ZXM, 2ZXN, 3A2H, 3AFR, 3AUN, 3VJS, 3VJT, 3VRT, 3VRU, 3VRV, 3VRW, 3VT4, 3VT5, 3VT7, 3VT8, 3VT9, 3VTB, 3VTC, 3VTD, 3W0G, 3W0H, 3W0I, 3W0J, 3W5P, 3W5Q, 3W5R, 3W5T, 3WT5, 3WT7 N/A link
P15207 Rattus norvegicus Androgen receptor Ar DHT, HYQ, LG7, 8NH, LGB 1I37, 1XNN, 2IHQ, 2NW4, 3G0W N/A link
P22449 Rattus norvegicus Hepatocyte nuclear factor 4-alpha Hnf4a DAO 1M7W N/A link
P45446 Rattus norvegicus Nuclear receptor ROR-beta Rorb STE, REA, ARL 1K4W, 1N4H, 1NQ7 N/A link
Q62735 Rattus norvegicus Bile acid receptor Nr1h4 CHC, IU5 1OSV, 1OT7 N/A link
Q62986 Rattus norvegicus Estrogen receptor beta Esr2 AOE, RAL, EST, E3O 1HJ1, 1QKN, 2J7X, 2J7Y N/A link
Q9Z2F5 Rattus norvegicus C-terminal-binding protein 1 Ctbp1 NAD 1HKU N/A link
O68014 Acinetobacter baylyi HTH-type transcriptional regulator BenM benM BEZ, CCU 2F78, 2F7A N/A link
P07774 Acinetobacter baylyi HTH-type transcriptional regulator CatM catM CCU 2F7C N/A link
Q7X0D9 Acinetobacter baylyi HcaR protein hcaR HC4, V55, FER, DHB 4RGR, 4RGS, 4RGU, 4RGX N/A link
A9CIH8 Agrobacterium tumefaciens Transcriptional regulator, AsnC family Atu1885 ACT 3I4P N/A link
A6TKU5 Alkaliphilus metalliredigens Periplasmic binding protein/LacI transcriptional regulator Amet_0586 XLF 3CTP N/A link
O67198 Aquifex aeolicus Transcriptional regulator (NtrC family) ntrC1 ADP, ATP, 08T 1NY5, 3M0E, 4LZZ N/A link
A0K1X3 Arthrobacter sp. Transcriptional regulator, LacI family Arth_3918 LBT 4RKR N/A link
P46828 Bacillus megaterium. Catabolite control protein A ccpA BG6, FBP 2NZU, 2NZV N/A link
Q3AB29 Carboxydothermus hydrogenoformans Carbon monoxide oxidation system transcription regulator cooA-1 HEM 2FMY N/A link
A9WGF5 Chloroflexus aurantiacus Helix-turn-helix domain protein Caur_2278 MYR 3PXP N/A link
Q7NQP7 Chromobacterium violaceum Transcriptional activator, LuxR/UhpA family of regulators cviR HL6, HL0 3QP6, 3QP8 N/A link
D3W065 Chromobacterium violaceum. CviR transcriptional regulator cviR HL6, HTF, HL0, HLC 3QP1, 3QP2, 3QP4, 3QP5 N/A link
P12529 Citrobacter freundii. HTH-type transcriptional activator AmpR ampR MES 3KOS N/A link
P94678 Comamonas testosteroni HTH-type transcriptional regulator TsaR tsaR TSU 3N6U N/A link
H7C677 Corynebacterium glutamicum Full=Probable transcription regulator N/A CMP 4CYD N/A link
Q79VI7 Corynebacterium glutamicum Corynebacterium glutamicum ATCC 13032, IS fingerprint type 4-5, complete genome; segment 1/10 cg0350 CMP 3R6S N/A link
Q8NLJ5 Corynebacterium glutamicum Corynebacterium glutamicum ATCC 13032, IS fingerprint type 4-5, complete genome; segment 9/10 cg3261 MPD 2DU9 N/A link
Q9PTN2 Danio rerio Vitamin D3 receptor A vdra XE4, VDX, C5D, G72, H97, 0U3, 0S4, 0VK, 0VO, 0VP, 484, 0VQ, BIV, 4OA 2HBH, 2HC4, 3DR1, 3O1D, 3O1E, 4FHH, 4FHI, 4G1D, 4G1Y, 4G1Z, 4G20, 4G2H, 4IA1, 4Q0A N/A link
B8J364 Desulfovibrio desulfuricans Putative transcriptional regulator, AsnC family Ddes_0286 OBV 4UN1 N/A link
P20153 Drosophila melanogaster Protein ultraspiracle usp LPP 1HG4 N/A link
Q82ZT5 Enterococcus faecalis Sugar-binding transcriptional regulator, LacI family EF_2962 RIB 4RK0 N/A link
I3TZ89 Enterococcus faecium DO. Ribose transcriptional regulator rbsR RIB 4RK1 N/A link
Q2NB98 Erythrobacter litoralis Sensor histidine kinase ELI_04755 FMN 3P7N N/A link
P04625 Gallus gallus Thyroid hormone receptor alpha THRA T3 3UVV N/A link
O31408 Geobacillus stearothermophilus Arginine repressor argR ARG 1B4B N/A link
Q746X3 Geobacter sulfurreducens Proline dehydrogenase and Delta-1-pyrroline-5-carboxylate dehydrogenase putA FAD 4NM9 N/A link
B9UCQ4 Helicoverpa armigera Ecdysone receptor N/A 834 3IXP N/A link
O18473 Heliothis virescens Ecdysone receptor EcR P1A, HWG, 20E 1R1K, 1R20, 2R40 N/A link
Q7SIF6 Heliothis virescens Gene regulation protein N/A EPH 1G2N N/A link
Q036L9 Lactobacillus casei Transcriptional regulator, LacI family LSEI_2103 GLC, SUC, TRS 4RK4, 4RK5, 4WXE N/A link
O26413 Methanothermobacter thermautotrophicus Transcriptional regulator MTH_313 SAL 3BPX N/A link
P96896 Mycobacterium tuberculosis Leucine-responsive regulatory protein lrp PHE, HIS, TYR, TRP, LEU, MET, LYS 2VBW, 2VBX, 2VBY, 2VBZ, 2VC0, 2VC1, 2W24 N/A link
P9WPY9 Mycobacterium tuberculosis Arginine repressor argR ARG, GGB 2ZFZ, 3LAP N/A link
Q9K0L9 Neisseria meningitidis serogroup B Transcriptional regulator, AsnC family NMB0573 MET, LEU 2P6S, 2P6T N/A link
P0A4U6 Nostoc sp. Global nitrogen regulator ntcA AKG, 2FT, BOG 3LA2, 3LA3, 3LA7 N/A link
O97775 Pan troglodytes Androgen receptor AR DHT 1T7R N/A link
E0VFQ5 Pediculus humanus subsp. corporis Retinoid X receptor, putative Phum_PHUM164330 NEQ 4OZT N/A link
E0VVT4 Pediculus humanus subsp. corporis Ecdysone receptor, putative Phum_PHUM467460 P1A 4OZT N/A link
P25084 Pseudomonas aeruginosa Transcriptional activator protein LasR lasR OHN, TX1, TX3, TY4 3IX3, 3IX4, 3IX8, 3JPU N/A link
P55222 Pseudomonas aeruginosa Cyclic AMP receptor-like protein vfr CMP 2OZ6 N/A link
Q9RMS5 Pseudomonas aeruginosa. PhzR phzR OHN 3SZT N/A link
Q88PQ6 Pseudomonas putida Fructose transport system repressor FruR fruR F1X 3O75 N/A link
O59188 Pyrococcus horikoshii Uncharacterized HTH-type transcriptional regulator PH1519 PH1519; GLN, ARG, LYS 2CYY, 2ZNY, 2ZNZ N/A link
P33905 Rhizobium radiobacter Transcriptional activator protein TraR traR HSL-OOA, LAE 1H0M, 1L3L N/A link
P55407 Rhizobium sp. Probable transcriptional activator protein TraR traR LAE 2Q0O N/A link
Q2RUG3 Rhodospirillum rubrum Transcriptional regulator, Crp/Fnr family Rru_A1431 HEM 4K8F N/A link
P72322 Rhodospirillum rubrum. CooA protein cooA HEM 1FT9 N/A link
P03069 Saccharomyces cerevisiae General control protein GCN4 GCN4 C2E-C2E 3I5C N/A link
P06614 Salmonella typhimurium HTH-type transcriptional regulator CysB cysB OAS, SAC 4LQ2, 4M4G N/A link
P25852 Salmonella typhimurium Transcriptional regulatory protein ZraR zraR ATP 1OJL N/A link
P40676 Salmonella typhimurium Transcriptional regulator SlyA slyA SAL 3DEU N/A link
P52679 Sphingobium chlorophenolicum. PCP degradation transcriptional activation protein pcpR PCI, T6C 4RPN, 4RPO N/A link
P0A0N3 Staphylococcus aureus HTH-type transcriptional regulator QacR qacR MGR, ET, RHQ, DEQ, BER 3BQZ, 3BR3, 3BR5, 3BT9, 3BTI N/A link
Q6GEG9 Staphylococcus aureus Uncharacterized HTH-type transcriptional regulator SAR2349 SAR2349 KAN, SAL 4EM0, 4EM2 N/A link
P0A0N4 Staphylococcus aureus. HTH-type transcriptional regulator QacR qacR DEQ, CVI, BER, MGR, RHQ, PRL, ET, PNT, DID, BRN 1JT6, 1JTX, 1JUM, 1JUP, 1JUS, 1QVT, 1QVU, 1RKW, 1RPW, 2GBY N/A link
Q5HLN6 Staphylococcus epidermidis Transcriptional regulator TcaR tcaR PNN, AIC, MII, KAN, SAL, SRY 3KP2, 3KP3, 3KP4, 3KP5, 3KP6, 4EJV, 4EJW N/A link
P0A0N5 Staphylococcus haemolyticus. HTH-type transcriptional regulator QacR qacR CGQ 2G0E N/A link
Q8E565 Streptococcus agalactiae serotype III Redox-sensing transcriptional repressor Rex rex NAD 3KEO N/A link
Q9ADP7 Streptomyces coelicolor HTH-type transcriptional repressor SCO4008 SCO4008; TLA 2D6Y N/A link
Q9L2B5 Streptomyces coelicolor Putative transcriptional regulator SCO5405 SAL 3ZMD N/A link
Q9XAM6 Streptomyces coelicolor Putative transcriptional regulator SCO6704 DHB 4FHT N/A link
Q9XZJ5 Strongyloides stercoralis Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily N/A DL4, DL7 3GYT, 3GYU N/A link
F9VNT4 Sulfolobus tokodaii Glutamine receptor protein grp GLN 2PN6 N/A link
Q96ZY1 Sulfolobus tokodaii Putative MarR family transcriptional regulator STK_17100 SAL 3GF2 N/A link
P29283 Synechococcus elongatus Global nitrogen regulator ntcA AKG 2XKO N/A link
D5KM69 Thermoanaerobacter ethanolicus JW 200. Redox-sensing transcriptional repressor Rex rex 8NA, NAI, NAJ 3WGG, 3WGH, 3WGI N/A link
Q9X2V5 Thermus aquaticus. Redox-sensing transcriptional repressor Rex rex NAD 1XCB N/A link
Q5SHS3 Thermus thermophilus Redox-sensing transcriptional repressor Rex rex NAD 2DT5 N/A link
Q5SID7 Thermus thermophilus Transcription regulator, Crp family TTHA1437 CMP 4EV0 N/A link
Q72I39 Thermus thermophilus Redox-sensing transcriptional repressor Rex rex NAD 3IKT N/A link
A1JUG3 Tribolium castaneum Ecdysone receptor ecr-a P1A 2NXX N/A link
Q9NCL0 Tribolium castaneum Tailless ortholog N/A MAL 4XAI N/A link
A5F384 Vibrio cholerae serotype O1 TCP pilus virulence regulatory protein tcpN PAM 3GBG N/A link
Q9KKZ8 Vibrio cholerae serotype O1 Transcriptional regulator, LuxR family VC_A0952 C2E-C2E 3KLO N/A link
Q9KQU8 Vibrio cholerae serotype O1 Fatty acid metabolism regulator protein {ECO:0000255|HAMAP-Rule:MF_00696} fadR 3VV 4PDK N/A link
Q7MD38 Vibrio vulnificus Transcriptional regulator VVA1198 BMX 4IVN N/A link
C5RBT0 Weissella paramesenteroides ATCC 33313. Glucose-resistance amylase regulator ccpA GLC, SUC 4RK6, 4RK7 N/A link